Article
A genome-wide association study identifies a locus for nonsyndromic cleft lip with or without cleft palate on 8q24.
The Journal of pediatrics - 1 Dec 2009
Grant Struan F A, Wang Kai, Zhang Haitao, Glaberson Wendy, Annaiah Kiran, Kim Cecilia E, Bradfield Jonathan P, Glessner Joseph T, Thomas Kelly A, Garris Maria, Frackelton Edward C, Otieno F George, Chiavacci Rosetta M, Nah Hyun-Duck, Kirschner Richard E, Hakonarson Hakon
Abstract excerpt
OBJECTIVE: To identify, in a non-hypothesis manner, novel genetic factors associated with nonsyndromic cleft lip with or without cleft palate (NSCL/P). STUDY DESIGN: We performed a genome-wide association study in a pediatric cohort of European decent consisting of 111 NSCL/P cases and 5951 control subjects. All subjects were consecutively recruited from the Greater Philadelphia area from 2006 to 2009. High...
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