Article
Motivational learning biases are differentially modulated by genetic determinants of striatal and prefrontal dopamine function.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Nov 2021
Richter Anni, de Boer Lieke, Guitart-Masip Marc, Behnisch Gusalija, Seidenbecher Constanze I, Schott Björn H
Abstract excerpt
Dopaminergic neurotransmission plays a pivotal role in appetitively motivated behavior in mammals, including humans. Notably, action and valence are not independent in motivated tasks, and it is particularly difficult for humans to learn the inhibition of an action to obtain a reward. We have previously observed that the carriers of the DRD2/ANKK1 TaqIA A1 allele, that has been associated with reduced striatal...
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