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Article

The effects of COMT (Val108/158Met) and DRD4 (SNP -521) dopamine genotypes on brain activations related to valence and magnitude of rewards.

Cerebral cortex (New York, N.Y. : 1991) - 1 Aug 2010

Camara Estela, Krämer Ulrike M, Cunillera Toni, Marco-Pallarés Josep, Cucurell David, Nager Wido, Mestres-Missé Anna, Bauer Peter, Schüle Rebecca, Schöls Ludger, Tempelmann Claus, Rodriguez-Fornells Antoni, Münte Thomas F

Abstract excerpt

People's sensitivity to reinforcing stimuli such as monetary gains and losses shows a wide interindividual variation that might in part be determined by genetic differences. Because of the established role of the dopaminergic system in the neural encoding of rewards and negative events, we invest...

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Source

Identifiers

PMID: 20038544
DOI: 10.1093/cercor/bhp263

Genes

COMT
DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20038544-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The effects of COMT (Val108/158Met) and DRD4 (SNP -521) dopamine genotypes on brain activations related to valence and magnitude of rewards.PMID 20038544Read ↗

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