Article
Identification and physical characterization of a spontaneous mutation of the tobacco mosaic virus in the laboratory environment.
Scientific reports - 23 Jul 2021
Lumata Jenica L, Ball Darby, Shahrivarkevishahi Arezoo, Luzuriaga Michael A, Herbert Fabian C, Brohlin Olivia, Lee Hamilton, Hagge Laurel M, D'Arcy Sheena, Gassensmith Jeremiah J
Abstract excerpt
Virus-like particles are an emerging class of nano-biotechnology with the Tobacco Mosaic Virus (TMV) having found a wide range of applications in imaging, drug delivery, and vaccine development. TMV is typically produced in planta, and, as an RNA virus, is highly susceptible to natural mutation that may impact its properties. Over the course of 2 years, from 2018 until 2020, our laboratory followed a spontaneous...
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