Identification of viral mutants by mass spectrometry.

doi:10.1073/pnas.95.15.8596

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Article

Identification of viral mutants by mass spectrometry.

Proceedings of the National Academy of Sciences of the United States of America - 21 Jul 1998

Lewis J K, Bendahmane M, Smith T J, Beachy R N, Siuzdak G

Abstract excerpt

A method to identify mutations of virus proteins by using protein mass mapping is described. Comparative mass mapping was applied to a structural protein of the human rhinovirus Cys1199 --> Tyr mutant and to genetically engineered mutants of tobacco mosaic virus. The information generated from th...

Topics

Amino Acid Sequence
Amino Acid Substitution
DNA, Viral
Databases, Factual
Fourier Analysis
Molecular Sequence Data
Mutation
Plants, Toxic
Rhinovirus
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Nicotiana
Tobacco Mosaic Virus
Viral Proteins

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Identifiers

PMID: 9671723
DOI: 10.1073/pnas.95.15.8596
PMCID: PMC21121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9671723-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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