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Article

The Genomic Landscape of a Restricted ALL Cohort from Patients Residing on the U.S./Mexico Border.

International journal of environmental research and public health - 9 Jul 2021

Grant Alice Hernandez, Ayala-Marin Yoshira Marie, Mohl Jonathon Edward, Robles-Escajeda Elisa, Rodriguez Georgialina, Dutil Julie, Kirken Robert Arthur

Abstract excerpt

Next-generation sequencing (NGS) has identified unique biomarkers yielding new strategies in precision medicine for the treatment of Acute lymphoblastic leukemia (ALL). Hispanics show marked health disparities in ALL, often absent in clinical trials or cancer research. Thus, it is unknown whether Hispanics would benefit equally from curated data currently guiding precision oncology. Using whole-exome sequencing,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34299796
DOI: 10.3390/ijerph18147345
PMCID: PMC8307122

Genes

NOTCH2
KRAS
ROS1
STAT5B
WT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

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Research trail→

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The Genomic Landscape of a Restricted ALL Cohort from Patients Residing on the U.S./Mexico Border.PMID 34299796Read ↗

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ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Genetic variants in ARID5B and CEBPE are childhood ALL susceptibility loci in Hispanics.Semantic proximity Read ↗

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