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Article

Chromatin Profiling Techniques: Exploring the Chromatin Environment and Its Contributions to Complex Traits.

International journal of molecular sciences - 16 Jul 2021

Chawla Anjali, Nagy Corina, Turecki Gustavo

Abstract excerpt

The genetic architecture of complex traits is multifactorial. Genome-wide association studies (GWASs) have identified risk loci for complex traits and diseases that are disproportionately located at the non-coding regions of the genome. On the other hand, we have just begun to understand the regulatory roles of the non-coding genome, making it challenging to precisely interpret the functions of non-coding...

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PMID: 34299232
DOI: 10.3390/ijms22147612
PMCID: PMC8305586

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