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Article

Wild-Type and Mutant FUS Expression Reduce Proliferation and Neuronal Differentiation Properties of Neural Stem Progenitor Cells.

International journal of molecular sciences - 15 Jul 2021

Stronati Eleonora, Biagioni Stefano, Fiore Mario, Giorgi Mauro, Poiana Giancarlo, Toselli Camilla, Cacci Emanuele

Abstract excerpt

Nervous system development involves proliferation and cell specification of progenitor cells into neurons and glial cells. Unveiling how this complex process is orchestrated under physiological conditions and deciphering the molecular and cellular changes leading to neurological diseases is mandatory. To date, great efforts have been aimed at identifying gene mutations associated with many neurodegenerative...

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Identifiers

PMID: 34299185
DOI: 10.3390/ijms22147566
PMCID: PMC8304973

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