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Article

Functions of FUS/TLS From DNA Repair to Stress Response: Implications for ALS

1 May 2014

Abstract excerpt

Fused in sarcoma/translocated in liposarcoma (FUS/TLS or FUS) is a multifunctional DNA-/RNA-binding protein that is involved in a variety of cellular functions including transcription, protein translation, RNA splicing, and transport. FUS was initially identified as a fusion oncoprotein, and thus, the early literature focused on the role of FUS in cancer. With the recent discoveries revealing the role of FUS in...

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PMID: 25289647
DOI: 10.1177/1759091414544472

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