The Impact of Promoter Variants in Interleukin-18 on Susceptibility to Ankylosing Spondylitis in a Sample of Iraqi Patients.

doi:10.12688/f1000research.172631.2

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The Impact of Promoter Variants in Interleukin-18 on Susceptibility to Ankylosing Spondylitis in a Sample of Iraqi Patients.

F1000Research - 1 Jan 2025

Jasim Ibtehal Kadhim, Saud Asmaa Mohammed

Abstract excerpt

Background: Ankylosing spondylitis (AS) is a chronic inflammatory illness mainly influencing the axial skeleton. It is a multifactorial illness in which environmental and genetic parameters contribute to its cause, one of which is interleukins, including interleukin-18 (IL-18). Therefore, this study aimed to investigate the association between single nucleotide polymorphism (SNP) rs549908 and serum levels of...

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PMID: 42077498
DOI: 10.12688/f1000research.172631.2
PMCID: PMC13133617

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