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Article

Genetic analysis implicates a molecular chaperone complex in regulating epigenetic silencing of methylated genomic regions.

Journal of integrative plant biology - 1 Aug 2021

Feng Zhengyan, Zhan Xiangqiang, Pang Jia, Liu Xue, Zhang Huiming, Lang Zhaobo, Zhu Jian-Kang

Abstract excerpt

DNA cytosine methylation confers stable epigenetic silencing in plants and many animals. However, the mechanisms underlying DNA methylation-mediated genomic silencing are not fully understood. We conducted a forward genetic screen for cellular factors required for the silencing of a heavily methylated p35S:NPTII transgene in the Arabidopsis thaliana rdm1-1 mutant background, which led to the identification of a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34289245
DOI: 10.1111/jipb.13155

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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