Article
Disruption of the plant gene MOM releases transcriptional silencing of methylated genes.
Nature - 11 May 2000
Amedeo P, Habu Y, Afsar K, Mittelsten Scheid O, Paszkowski J
Abstract excerpt
Epigenetic modifications change transcription patterns in multicellular organisms to achieve tissue-specific gene expression and inactivate alien DNA such as transposons or transgenes. In plants and animals, DNA methylation is involved in heritability and flexibility of epigenetic states, although its function is far from clear. We have isolated an Arabidopsis gene, MOM, whose product is required for the...
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