Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alterations of Growth and Focal Adhesion Molecules in Human Breast Cancer Cells Exposed to the Random Positioning Machine

30 Jun 2021

Abstract excerpt

In this study, we evaluated changes in focal adhesions (FAs) in two types of breast cancer cell (BCC) lines (differentiated MCF-7 and the triple-negative MDA-MB-231 cell line) exposed to simulated microgravity (s-μg) created by a random positioning machine (RPM) for 24 h. After exposure, the BCC changed their growth behavior and exhibited two phenotypes in RPM samples: one portion of the cells grew as a normal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cellular Mechanics and Interactions
Share to Electromagnetic Fields and Biological Effects
Share to Spaceflight effects on biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34277614
DOI: 10.3389/fcell.2021.672098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alterations of Growth and Focal Adhesion Molecules in Human Breast Cancer Cells Exposed to the Random Positioning MachinePMID 34277614Read ↗

Long-Term Simulation of Microgravity Induces Changes in Gene Expression in Breast Cancer CellsSemantic proximity Read ↗

Short-term effects of simulated microgravity on morphology and gene expression in human breast cancer cells.Semantic proximity Read ↗

Identifications of novel mechanisms in breast cancer cells involving duct-like multicellular spheroid formation after exposure to the Random Positioning Machine.Semantic proximity Read ↗

Decreased E‐Cadherin in MCF7 Human Breast Cancer Cells Forming Multicellular Spheroids Exposed to Simulated MicrogravitySemantic proximity Read ↗

Pathways Regulating Spheroid Formation of Human Follicular Thyroid Cancer Cells under Simulated Microgravity Conditions: A Genetic ApproachSemantic proximity Read ↗

Proteome Analysis of Human Follicular Thyroid Cancer Cells Exposed to the Random Positioning MachineSemantic proximity Read ↗

Apoptosis Induction and Alteration of Cell Adherence in Human Lung Cancer Cells under Simulated MicrogravitySemantic proximity Read ↗

Reduced Expression of Cytoskeletal and Extracellular Matrix Genes in Human Adult Retinal Pigment Epithelium Cells Exposed to Simulated Microgravity.Semantic proximity Read ↗

The role of NFκB in spheroid formation of human breast cancer cells cultured on the Random Positioning MachineSemantic proximity Read ↗

Phenotypic switch induced by simulated microgravity on MDA-MB-231 breast cancer cells.Semantic proximity Read ↗

Simulated microgravity induces HIF-1-dependent pseudohypoxic and glycolytic state in triple- negative breast cancerSemantic proximity Read ↗

The Fight against Cancer by Microgravity: The Multicellular Spheroid as a Metastasis ModelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.