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The role of NFκB in spheroid formation of human breast cancer cells cultured on the Random Positioning Machine

11 Jan 2018

Abstract excerpt

Human MCF-7 breast cancer cells were exposed to a Random Positioning Machine (RPM). After 24 hours (h) the cells grew either adherently within a monolayer (AD) or within multicellular spheroids (MCS). AD and MCS populations were separately harvested, their cellular differences were determined performing qPCR on genes, which were differently expressed in AD and MCS cells. Gene array technology was applied to...

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PMID: 29343717
DOI: 10.1038/s41598-017-18556-8

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