Article
Unhealthy Behaviours and Risk of Parkinson's Disease: A Mendelian Randomisation Study.
Journal of Parkinson's disease - 1 Jan 2021
Heilbron Karl, Jensen Melanie P, Bandres-Ciga Sara, Fontanillas Pierre, Blauwendraat Cornelis, Nalls Mike A, Singleton Andrew B, Smith George Davey, Cannon Paul, Noyce Alastair J
Abstract excerpt
BACKGROUND: Tobacco smoking and alcohol intake have been identified in observational studies as potentially protective factors against developing Parkinson's disease (PD); the impact of body mass index (BMI) on PD risk is debated. Whether such epidemiological associations are causal remains unclear. Mendelian randomsation (MR) uses genetic variants to explore the effects of exposures on outcomes; potentially...
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