Protective Evidence for Alcohol Consumption in Parkinson’s Disease Risk and Associated Genes of DPP6, SLC39A8, MAD1L1, and RBFOX1

Abstract excerpt

<title>Abstract</title> <p>Background Parkinson’s disease (PD), a leading neurodegenerative disorder, is increasing in prevalence globally due to population ageing. Although alcohol consumption is widespread worldwide, its role in PD pathogenesis remains contentious, with studies reporting both protective and harmful associations. Methods Here, we integrate familial, population-based, and genomic data to invest...

Topics

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• Alcohol Drinking
• Data Analysis
• Disease Susceptibility
• Drinking Behavior
• Mendelian Randomization Analysis
• Odds Ratio
• Parkinson Disease
• Tobacco Smoking

Identifiers and source

Literature Corpus work

5815e220-e2ca-5bc5-b81d-bfb0d51f6f9e

DOI

10.21203/rs.3.rs-6754726/v1