Article
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools.
Brain : a journal of neurology - 29 Mar 2022
Bahrami Shahram, Hindley Guy, Winsvold Bendik Slagsvold, O'Connell Kevin S, Frei Oleksandr, Shadrin Alexey, Cheng Weiqiu, Bettella Francesco, Rødevand Linn, Odegaard Ketil J, Fan Chun C, Pirinen Matti J, Hautakangas Heidi M, Dale Anders M, Djurovic Srdjan, Smeland Olav B, Andreassen Ole A
Abstract excerpt
Migraine is three times more prevalent in people with bipolar disorder or depression. The relationship between schizophrenia and migraine is less certain although glutamatergic and serotonergic neurotransmission are implicated in both. A shared genetic basis to migraine and mental disorders has been suggested but previous studies have reported weak or non-significant genetic correlations and five shared risk...
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