Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Additional mutations in IDH1/2-mutated patients with acute myeloid leukemia.

International journal of laboratory hematology - 1 Dec 2021

Lu Jingtao, Chen Meiyu, Hua Haiying, Qin Wei, Zhang Ri, Lu Xuzhang, Chao Hongying

Abstract excerpt

OBJECTIVE: Somatic mutations in isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) frequently emerge in acute myeloid leukemia (AML), but the clinical features and molecular characteristics of IDH mutational status and other coexisting mutations have not been investigated in a large extensively characterized AML series. The aim of this study was to gain insight into the mutational profile of IDH-mutated patients,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Leukemia, Myeloid, Acute
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

Share to Gene Frequency

Share to Genetic Association Studies

Share to Isocitrate Dehydrogenase

Share to Leukocyte Count

Share to Prognosis

Source

Identifiers

PMID: 34270876
DOI: 10.1111/ijlh.13648

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Additional mutations in IDH1/2-mutated patients with acute myeloid leukemia.PMID 34270876Read ↗

Differential impact of IDH1/2 mutational subclasses on outcome in adult AML: results from a large multicenter study.Semantic proximity Read ↗

Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value.Semantic proximity Read ↗

Acute myeloid leukemia with IDH1 or IDH2 mutation: frequency and clinicopathologic features.Semantic proximity Read ↗

IDH1/2 mutations in acute myeloid leukemiaSemantic proximity Read ↗

IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication.Semantic proximity Read ↗

Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients.Semantic proximity Read ↗

IDH2 mutations in acute myeloid leukemia.Semantic proximity Read ↗

Prevalence and Prognostic Role of IDH Mutations in Acute Myeloid Leukemia: Results of the GIMEMA AML1516 ProtocolSemantic proximity Read ↗

Prognostic significance of concurrent gene mutations in intensively treated patients withIDH-mutated AML: an ALFA studySemantic proximity Read ↗

IDH mutations in acute myeloid leukemia.Semantic proximity Read ↗

IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.Semantic proximity Read ↗

IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia and associated with NPM1 mutations and FAB-M2 subtype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.