Article
Genetic variants associated with cytomegalovirus infection after allogeneic hematopoietic cell transplantation.
Blood - 28 Oct 2021
Casto Amanda M, Seo Sachiko, Levine David M, Storer Barry E, Dong Xinyuan, Hansen John A, Boeckh Michael, Martin Paul J
Abstract excerpt
Human cytomegalovirus (CMV) reactivation is a frequent complication of allogeneic hematopoietic cell transplantation (HCT). Despite routine screening for CMV reactivation and early antiviral treatment, the rates of CMV-related complications after HCT remain high. Genetic variants in both the donor and recipient have been associated with the risk of CMV reactivation and disease after HCT, but these associations...
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