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Article

Donor KIR genotype has a major influence on the rate of cytomegalovirus reactivation following T-cell replete stem cell transplantation.

Blood - 1 Feb 2006

Cook Mark, Briggs David, Craddock Charles, Mahendra Premini, Milligan Donald, Fegan Christopher, Darbyshire Philip, Lawson Sarah, Boxall Elizabeth, Moss Paul

Abstract excerpt

Reactivation of cytomegalovirus (CMV) is a common complication following allogeneic stem cell transplantation. Genetic determinants in the host and donor that may influence the rate of reactivation are currently unknown. Viral replication is controlled by T cells and natural killer (NK) cells and these share expression of killer immunoglobulin-like receptors (KIRs). We analyzed whether activatory KIRs carried by...

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Identifiers

PMID: 16239436
DOI: 10.1182/blood-2005-03-1039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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