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Article

Development of an Image-Based HCS-Compatible Method for Endothelial Barrier Function Assessment.

SLAS discovery : advancing life sciences R & D - 1 Oct 2021

Dubrovskyi Oleksii, Hasten Erica, Dudek Steven M, Flavin Michael T, Chan Leo Li-Ying

Abstract excerpt

The recent renascence of phenotypic drug discovery (PDD) is catalyzed by its ability to identify first-in-class drugs and deliver results when the exact molecular mechanism is partially obscure. Acute respiratory distress syndrome (ARDS) is a severe, life-threatening condition with a high mortality rate that has increased in frequency due to the COVID-19 pandemic. Despite decades of laboratory and clinical study,...

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Identifiers

PMID: 34269109
DOI: 10.1177/24725552211030900

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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