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Article

High-Content Imaging and Machine Learning Classify Phenotypical Change in Coronary Artery Endothelial Cells Caused by BPS.

International journal of molecular sciences - 3 Apr 2026

Ferariu Lavinia Eugenia, Movileanu Gheorghe, Gaggi Giulia, Ghinassi Barbara, Baldassarre Angela di, Credico Andrea Di

Abstract excerpt

Bisphenol S (BPS) is widely used as a replacement for bisphenol A, yet accumulating evidence suggests that it has comparable endocrine and cardiovascular toxicity. Here, we investigated whether prolonged low-dose BPS exposure induces subtle but classifiable phenotypic alterations in human coronary artery endothelial cells (HCAEC), using an end-to-end experimental and ML pipeline that spans cell culture,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41977438
DOI: 10.3390/ijms27073259
PMCID: PMC13073268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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