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Oil immersed lossless total analysis system for integrated RNA extraction and detection of SARS-CoV-2

14 Jul 2021

Abstract excerpt

The COVID-19 pandemic exposed difficulties in scaling current quantitative PCR (qPCR)-based diagnostic methodologies for large-scale infectious disease testing. Bottlenecks include lengthy multi-step processes for nucleic acid extraction followed by qPCR readouts, which require costly instrumentation and infrastructure, as well as reagent and plastic consumable shortages stemming from supply chain constraints....

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PMID: 34262053
DOI: 10.1038/s41467-021-24463-4

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