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Performance and workflow assessment of six nucleic acid extraction technologies for use in resource limited settings

18 Apr 2019

Abstract excerpt

Infectious disease nucleic acid amplification technologies (NAAT) have superior sensitivity, specificity, and rapid time to result compared to traditional microbiological methods. Recovery of concentrated, high quality pathogen nucleic acid (NA) from complex specimen matrices is required for optimal performance of several NA amplification/detection technologies such as polymerase chain reaction (PCR). Fully...

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PMID: 30998749
DOI: 10.1371/journal.pone.0215753

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