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Direct diagnostic testing of SARS-CoV-2 without the need for prior RNA extraction

28 Jan 2021

Abstract excerpt

The COVID-19 pandemic has resulted in an urgent need for a rapid, point of care diagnostic testing that could be rapidly scaled on a worldwide level. We developed and tested a highly sensitive and robust assay based on reverse transcription loop mediated isothermal amplification (RT-LAMP) that uses readily available reagents and a simple heat block using contrived spike-in and actual clinical samples. RT-LAMP...

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PMID: 33510181
DOI: 10.1038/s41598-021-81487-y

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