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Article

Effector Vγ9Vδ2 T cell response to congenital Toxoplasma gondii infection

13 Jul 2021

Abstract excerpt

A major γδ T cell population in human adult blood are the Vγ9Vδ2 T cells that are activated and expanded in a TCR-dependent manner by microbe-derived and endogenously derived phosphorylated prenyl metabolites (phosphoantigens). Vγ9Vδ2 T cells are also abundant in human fetal peripheral blood, but compared with their adult counterparts they have a distinct developmental origin, are hyporesponsive toward in vitro...

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Share to Cytomegalovirus and herpesvirus research
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PMID: 34255746
DOI: 10.1172/jci.insight.138066

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