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Article

Germline and tumor BRCA1/2 pathogenic variants in Chinese triple-negative breast carcinomas.

Journal of cancer research and clinical oncology - 1 Oct 2021

Ji Gang, Bao Longlong, Yao Qianlan, Zhang Jing, Zhu Xiaoli, Bai Qianming, Shao Zhiming, Yang Wentao, Zhou Xiaoyan

Abstract excerpt

PURPOSE: BRCA1/2 screening for all triple-negative breast cancer (TNBC) patients younger than 60 years may still be an economic burden in China. Further evidences that include incidence and outcome of BRCA1/2 pathogenic variants (PV) screened based on younger age or family history (FH) are worth discussing for improving the cost-effectiveness of BRCA1/2 testing in Chinese TNBC. We aimed to investigate the...

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Identifiers

PMID: 34254208
DOI: 10.1007/s00432-021-03696-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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