Article
The application of the self-probing primer PCR for quantitative expression analysis of R607Q (un)edited GluA2 AMPA receptor mRNA.
Biochemical and biophysical research communications - 10 Sept 2021
Schwarz Alexander P, Kovalenko Anna A, Zakharova Maria V, Zaitsev Aleksey V
Abstract excerpt
Adenosine deaminase-dependent RNA editing is a widespread universal mechanism of posttranscriptional gene function modulation. Changes in RNA editing level may contribute to various physiological and pathological processes. In the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) glutamate receptor GluA2 subunit, A-I editing in the Q607R site leads to dramatic changes in function, making the receptor...
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