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Article

Multigene Panel Testing in Individuals With Hepatocellular Carcinoma Identifies Pathogenic Germline Variants.

JCO precision oncology - 1 Jan 2021

Mezina Anya, Philips Neil, Bogus Zoe, Erez Noam, Xiao Rui, Fan Ruoming, Olthoff Kim M, Reddy K Rajender, Samadder N Jewel, Nielsen Sarah M, Hatchell Kathryn E, Esplin Edward D, Rustgi Anil K, Katona Bryson W, Hoteit Maarouf A, Nathanson Katherine L, Wangensteen Kirk J

Abstract excerpt

Hepatocellular carcinoma (HCC) has well-defined environmental risk factors. In addition, epidemiologic studies have suggested hereditary risk factors. The goals of this study were to determine the rate of pathogenic and likely pathogenic (P/LP) germline variants in cancer predisposition genes in patients with HCC, possible enrichment of P/LP variants in particular genes, and potential impact on clinical...

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Identifiers

PMID: 34250406
DOI: 10.1200/PO.21.00079
PMCID: PMC8232566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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