Article
The Low-Expression Variant of FABP4 Is Associated With Cardiovascular Disease in Type 1 Diabetes.
Diabetes - 1 Oct 2021
Dahlström Emma H, Saksi Jani, Forsblom Carol, Uglebjerg Nicoline, Mars Nina, Thorn Lena M, Harjutsalo Valma, Rossing Peter, Ahluwalia Tarunveer S, Lindsberg Perttu J, Sandholm Niina, Groop Per-Henrik
Abstract excerpt
Fatty acid binding protein 4 (FABP4) is implicated in the pathogenesis of cardiometabolic disorders. Pharmacological inhibition or genetic deletion of FABP4 improves cardiometabolic health and protects against atherosclerosis in preclinical models. As cardiovascular disease (CVD) is common in type 1 diabetes, we examined the role of FABP4 in the development of complications in type 1 diabetes, focusing on a...
Topics
Join the communities discussing this publication.
