Article
FABP4 plasma concentrations are determined by acquired metabolic derangements rather than genetic determinants.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Sept 2015
Ibarretxe D, Girona J, Plana N, Cabré A, Heras M, Ferré R, Merino J, Vallvé J C, Masana L
Abstract excerpt
BACKGROUND AND AIMS: Circulating FABP4 is strongly associated with metabolic and cardiovascular risk (CVR) and has been proposed as a new risk biomarker. Several FABP4 gene polymorphisms have been associated with protein expression in vitro and metabolic and vascular alterations in vivo. The aim of this study is to evaluate the impact of FABP4 polymorphisms on FABP4 plasma levels and subclinical arteriosclerosis...
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