Article
Electronic characteristics of BRCA1 mutations in DNA.
Biopolymers - 1 Aug 2021
He Lijun, Zhang Jinsha, He Chengyun, Zhao Boyang, Xie Zhiyang, Chen Weizhong, Sonawane Mahadev R, Patil Sunil R
Abstract excerpt
The efficient and low-cost way for gene mutation detection and identification are conducive for the detection of disease. Here, we report the electronic characteristics of the gene of breast cancer 1 in four common mutation types: duplication, single nucleotide variant, deletion, and indel. The electronic characteristics are investigated by the combination of density functional theory and non-equilibrium Green's...
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