Article
Charge transport properties of ideal and natural DNA segments, as mutation detectors.
Physical chemistry chemical physics : PCCP - 15 Mar 2023
Mantela Marilena, Lambropoulos Konstantinos, Simserides Constantinos
Abstract excerpt
DNA sequences of ideal and natural geometries are examined, studying their charge transport properties as mutation detectors. Ideal means textbook geometry. Natural means naturally distorted sequences; geometry taken from available databases. A tight-binding (TB) wire model at the base-pair level is recruited, together with a transfer matrix technique. The relevant TB parameters are obtained using a linear...
Topics
- Humans
- DNA
- Huntington Disease
- Mutation
- Adenine
- Guanine