Article
Ultrasensitive colorimetric biosensor for BRCA1 mutation based on multiple signal amplification strategy.
Biosensors & bioelectronics - 15 Oct 2020
Bai Yunfei, Li Huizhen, Xu Jun, Huang Yufan, Zhang Xiuming, Weng Jian, Li Zhu, Sun Liping
Abstract excerpt
Colorimetric biosensors have attracted wide attention due to their low cost, simple operation, rapid response and good reproducibility. However, insufficient sensitivity limits their applications. This report describes the design of a colorimetric biosensor based on a three-step multiple signal amplification strategy to detect breast cancer-associated BRCA1 mutation. The capture unit, signal unit, and target DNA...
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