Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Next-generation sequencing of BRCA1 and BRCA2 genes in Moroccan prostate cancer patients with positive family history.

PloS one - 1 Jan 2021

Salmi Fatiha, Maachi Fatima, Tazzite Amal, Aboutaib Rachid, Fekkak Jamal, Azeddoug Houssine, Jouhadi Hassan

Abstract excerpt

Prostate cancer is the most common male cancer in Morocco. Although sporadic forms account for a large proportion of patients, familial forms of prostate cancer are observed in 20% of cases and about 5% are due to hereditary transmission. Indeed, germline mutations in BRCA1/2 genes have been associated with prostate cancer risk. However, the spectrum of these mutations was not investigated in Moroccan Prostate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to BRCA1 Protein

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to BRCA2 Protein

Share to High-Throughput Nucleotide Sequencing

Share to Morocco

Share to Pedigree

Share to Polymorphism, Genetic

Share to Prostatic Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 34242281
DOI: 10.1371/journal.pone.0254101
PMCID: PMC8270444

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Next-generation sequencing of BRCA1 and BRCA2 genes in Moroccan prostate cancer patients with positive family history.PMID 34242281Read ↗

Review on the Role of BRCA Mutations in Genomic Screening and Risk Stratification of Prostate Cancer.Semantic proximity Read ↗

Germline BRCA1 mutations increase prostate cancer risk.Semantic proximity Read ↗

Analysis of BRCA Germline Mutations in Chinese Prostate Cancer PatientsSemantic proximity Read ↗

BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients.Semantic proximity Read ↗

Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.Semantic proximity Read ↗

Decreased prostate cancer-specific survival of men with BRCA2 mutations from multiple breast cancer families.Semantic proximity Read ↗

Prostate Cancer in a Patient with a Family History of BRCA Mutation: a Case Report and Literature Review.Semantic proximity Read ↗

The role of BRCA1 and BRCA2 in prostate cancer.Semantic proximity Read ↗

Increased risk of male cancer and identification of a potential prostate cancer cluster region in BRCA2.Semantic proximity Read ↗

Characterization of BRCA1 and BRCA2 genetic variants in a cohort of Bahraini breast cancer patients using next‐generation sequencingSemantic proximity Read ↗

Mutational spectrum of BRCA1/2 genes in Moroccan patients with hereditary breast and/or ovarian cancer, and review of BRCA mutations in the MENA region.Semantic proximity Read ↗

Screening of BRCA1/2 genes mutations and copy number variations in patients with high risk for hereditary breast and ovarian cancer syndrome (HBOC).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.