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Article

Decreased prostate cancer-specific survival of men with BRCA2 mutations from multiple breast cancer families.

Cancer prevention research (Philadelphia, Pa.) - 1 Jul 2011

Thorne Heather, Willems Amber J, Niedermayr Eveline, Hoh Ivan M Y, Li Jason, Clouston David, Mitchell Gillian, Fox Stephen, Hopper John L, Bolton Damien

Abstract excerpt

The role of a germ-line BRCA2 mutation in the development of prostate cancer is established, but the clinical presentation linked to outcome for this group of men has not been well described. A total of 148 men from 1,423 families were ascertained from the kConFab consortium. Each participant met the following criteria: (i) a verified case of prostate cancer; (ii) confirmed as either a carrier or noncarrier of a...

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Identifiers

PMID: 21733824
DOI: 10.1158/1940-6207.CAPR-10-0397

Genes

BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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