Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Parkinson's Disease Genetics and Pathophysiology

8 Jul 2021

Abstract excerpt

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by degeneration of the substantia nigra pars compacta and by accumulation of α-synuclein in Lewy bodies. PD is caused by a combination of environmental factors and genetic variants. These variants range from highly penetrant Mendelian alleles to alleles that only modestly increase disease risk. Here, we review what is known about the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lysosomal Storage Disorders Research
Share to Neurological diseases and metabolism
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34236893
DOI: 10.1146/annurev-neuro-100720-034518

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Parkinson's Disease Genetics and PathophysiologyPMID 34236893Read ↗

Genetics and Pathogenesis of Parkinson's Syndrome.Semantic proximity Read ↗

Parkinson's disease: genetics and pathogenesis.Semantic proximity Read ↗

Genetics of Parkinson's disease and related disorders.Semantic proximity Read ↗

Updates on the Genetics of Parkinson's Disease: Clinical Implications and Future Treatment.Semantic proximity Read ↗

The genetics of Parkinson disease.Semantic proximity Read ↗

What genetics tells us about the causes and mechanisms of Parkinson's disease.Semantic proximity Read ↗

Genetics of Parkinson's disease and parkinsonism.Semantic proximity Read ↗

Genetics and genomics of Parkinson’s diseaseSemantic proximity Read ↗

Genetics of parkinsonismSemantic proximity Read ↗

Genetics of Parkinson disease.Semantic proximity Read ↗

Genetics of Parkinson's disease.Semantic proximity Read ↗

Parkinson Disease from Mendelian Forms to Genetic Susceptibility: New Molecular Insights into the Neurodegeneration Process.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.