Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Untangling the genetic link between type 1 and type 2 diabetes using functional genomics.

Scientific reports - 6 Jul 2021

Nyaga Denis M, Vickers Mark H, Jefferies Craig, Fadason Tayaza, O'Sullivan Justin M

Abstract excerpt

There is evidence pointing towards shared etiological features between type 1 diabetes (T1D) and type 2 diabetes (T2D) despite both phenotypes being considered genetically distinct. However, the existence of shared genetic features for T1D and T2D remains complex and poorly defined. To better understand the link between T1D and T2D, we employed an integrated functional genomics approach involving extensive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Mass Index
Share to Diabetes Mellitus, Type 1
Share to Drug Repositioning

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Regulatory Networks

Share to Genetic Pleiotropy

Share to Multifactorial Inheritance

Share to Protein Interaction Maps

Share to Transcription Factor 7-Like 2 Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 34230558
DOI: 10.1038/s41598-021-93346-x
PMCID: PMC8260770

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Untangling the genetic link between type 1 and type 2 diabetes using functional genomics.PMID 34230558Read ↗

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.Semantic proximity Read ↗

The TCF7L2 Locus: A Genetic Window Into the Pathogenesis of Type 1 and Type 2 DiabetesSemantic proximity Read ↗

Genetics of type 2 diabetes and potential clinical implications.Semantic proximity Read ↗

In silico functional and pathway analysis of risk genes and SNPs for type 2 diabetes in Asian population.Semantic proximity Read ↗

Genome-wide meta-analysis of genetic susceptible genes for Type 2 Diabetes.Semantic proximity Read ↗

Shared genetic risk contributes to type 1 and type 2 diabetes etiologySemantic proximity Read ↗

Type 1 Diabetes Mellitus-Associated Genetic Variants Contribute to Overlapping Immune Regulatory NetworksSemantic proximity Read ↗

Multi-omics characterization of type 2 diabetes associated genetic variationSemantic proximity Read ↗

Computational analyses of type 2 diabetes-associated loci identified by genome-wide association studies.Semantic proximity Read ↗

Colocalization of eQTLs With Type 2 Diabetes and Glycemic Traits Using Whole-Genome Sequences in Diverse Populations From the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program.Semantic proximity Read ↗

High-throughput Genetic Clustering of Type 2 Diabetes Loci Reveals Heterogeneous Mechanistic Pathways of Metabolic DiseaseSemantic proximity Read ↗

High-Resolution Genetic Maps Identify Multiple Type 2 Diabetes Loci at Regulatory Hotspots in African Americans and Europeans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.