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Risk of cardiovascular disease among women carrying BRCA mutations after risk-reducing bilateral salpingo-oophorectomy: A population-based study.

Gynecologic oncology - 1 Sept 2021

do Valle Helena Abreu, Kaur Paramdeep, Kwon Janice S, Cheifetz Rona, Dawson Lesa, Hanley Gillian E

Abstract excerpt

OBJECTIVE: Examine the risk of cardiovascular disease (CVD) following risk reducing bilateral salpingo-oophorectomy (RRBSO) among women with BRCA mutations. METHODS: In this retrospective population-based study in British Columbia, Canada, between 1996 and 2017, we compared the risk of CVD among women with known BRCA mutations who underwent RRBSO before the age of 50 (n = 360) with two groups of age-matched women...

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PMID: 34217543
DOI: 10.1016/j.ygyno.2021.06.022

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