Article
Bone health after RRBSO among BRCA1/2 mutation carriers: a population-based study.
Journal of gynecologic oncology - 1 Jul 2022
do Valle Helena Abreu, Kaur Paramdeep, Kwon Janice S, Cheifetz Rona, Dawson Lesa, Hanley Gillian E
Abstract excerpt
OBJECTIVE: Examine the risks of fractures and osteoporosis after risk-reducing bilateral salpingo-oophorectomy (RRBSO) among women with BRCA1/2 mutations. METHODS: In this retrospective population-based study in British Columbia, Canada, between 1996 to 2017, we compared risks of osteoporosis and fractures among women with BRCA1/2 mutations who underwent RRBSO before the age of 50 (n=329) with two age-matched...
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