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Article

BRCA1/2 mutation carriers are potentially at higher cardiovascular risk.

Critical reviews in oncology/hematology - 1 Aug 2014

Arts-de Jong M, Maas A H E M, Massuger L F, Hoogerbrugge N, de Hullu J A

Abstract excerpt

BRCA1/2 mutation carriers have an elevated risk of developing breast and ovarian cancer at a relatively young age. Risk-reducing salpingo-oophorectomy is an established strategy to tremendously reduce the risk of ovarian cancer. It is recommended to perform this surgery at age 35-40 years (BRCA1) and at age 40-45 years (BRCA2) resulting in an early and abrupt menopause. BRCA1/2 mutation carriers are potentially...

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Source

Identifiers

PMID: 24529552
DOI: 10.1016/j.critrevonc.2014.01.008

Genes

BRCA1
BRCA2

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