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Article

Cardiovascular risk of BRCA1/2 mutation carriers: A review.

Maturitas - 1 Sept 2016

van Westerop L L M, Arts-de Jong M, Hoogerbrugge N, de Hullu J A, Maas A H E M

Abstract excerpt

BRCA1/2 mutation carriers are at high risk of breast and ovarian cancer. The number of studies on non-cancer endpoints in BRCA1/2 mutation carriers is still limited. BRCA1/2 mutation carriers may be at higher cardiovascular risk due to early menopause after risk-reducing salpingo-oophorectomy and/or due to the potential cardiotoxic effects of breast cancer treatment (radiotherapy and chemotherapy). Moreover, BRCA...

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Source

Identifiers

PMID: 27451331
DOI: 10.1016/j.maturitas.2016.06.012

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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