Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combining mutation and horizontal gene transfer in a within-host model of antibiotic resistance.

Mathematical biosciences - 1 Sept 2021

Roberts M G, Burgess S, Toombs-Ruane L J, Benschop J, Marshall J C, French N P

Abstract excerpt

Antibiotics are used extensively to control infections in humans and animals, usually by injection or a course of oral tablets. There are several methods by which bacteria can develop antimicrobial resistance (AMR), including mutation during DNA replication and plasmid mediated horizontal gene transfer (HGT). We present a model for the development of AMR within a single host animal. We derive criteria for a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacteria
Share to Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Transfer, Horizontal

Share to Host Microbial Interactions

Share to Models, Biological

Share to Mutation

Share to Plasmids

Source

Identifiers

PMID: 34216634
DOI: 10.1016/j.mbs.2021.108656

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combining mutation and horizontal gene transfer in a within-host model of antibiotic resistance.PMID 34216634Read ↗

Within-host bacterial growth dynamics with both mutation and horizontal gene transfer.Semantic proximity Read ↗

Mobile elements, zoonotic pathogens and commensal bacteria: conduits for the delivery of resistance genes into humans, production animals and soil microbiotaSemantic proximity Read ↗

A mathematical model of antibiotic resistance gene flow from livestock and spread amongst humansSemantic proximity Read ↗

Emergence and spread of antibiotic resistance following exposure to antibiotics.Semantic proximity Read ↗

Antibiotic resistance in microbes.Semantic proximity Read ↗

Antibiotic resistance and virulence: Understanding the link and its consequences for prophylaxis and therapySemantic proximity Read ↗

Antibiotics in agriculture and the risk to human health: how worried should we be?Semantic proximity Read ↗

Modelling the synergistic effect of bacteriophage and antibiotics on bacteria: killers and drivers of resistance evolutionSemantic proximity Read ↗

Evolution and spread of antibiotic resistance.Semantic proximity Read ↗

Multi-step vs. single-step resistance evolution under different drugs, pharmacokinetics, and treatment regimens.Semantic proximity Read ↗

Mathematical modeling on bacterial resistance to multiple antibiotics caused by spontaneous mutations.Semantic proximity Read ↗

Augmented dissemination of antibiotic resistance elicited by non-antibiotic factorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.