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Article

Mathematical modeling on bacterial resistance to multiple antibiotics caused by spontaneous mutations.

Bio Systems - 1 Mar 2014

Ibargüen-Mondragón Eduardo, Mosquera Saulo, Cerón Miller, Burbano-Rosero Edith Mariela, Hidalgo-Bonilla Sandra P, Esteva Lourdes, Romero-Leitón Jhoana P

Abstract excerpt

We formulate a mathematical model that describes the population dynamics of bacteria exposed to multiple antibiotics simultaneously, assuming that acquisition of resistance is through mutations due to antibiotic exposure. Qualitative analysis reveals the existence of a free-bacteria equilibrium, resistant-bacteria equilibrium and an endemic equilibrium where both bacteria coexist.

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24467935
DOI: 10.1016/j.biosystems.2014.01.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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