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Essential oils modulate virulence phenotypes in a multidrug-resistant pyomelanogenic Pseudomonas aeruginosa clinical isolate.

Scientific reports - 30 Jan 2025

Haripriyan Jayalekshmi, Binu Christy Rose, Menon Nitasha D, Vanuopadath Muralidharan, Hari Malavika B, Namitha N, Binoy Kesiya, Kumar Anil, Nair Bipin G, Nizet Victor, Kumar Geetha B

Abstract excerpt

Pyomelanogenic P. aeruginosa, frequently isolated from patients with urinary tract infections and cystic fibrosis, possesses the ability to withstand oxidative stress, contributing to virulence and resulting in persistent infections. Whole genome sequence analysis of U804, a pyomelanogenic, multidrug-resistant, clinical isolate, demonstrates the mechanism underlying pyomelanin overproduction. Seven essential oils...

Topics

Pseudomonas aeruginosa
Oils, Volatile
Animals
Humans
Drug Resistance, Multiple, Bacterial
Virulence
Caenorhabditis elegans
Biofilms
Quorum Sensing
Anti-Bacterial Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microbial Sensitivity Tests

Pseudomonas Infections

Phenotype

Garlic

Source

Open in PubMed Open full text

Identifiers

PMID: 39885214
DOI: 10.1038/s41598-025-86515-9
PMCID: PMC11782693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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