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Biosynthetic gene cluster signature profiles of pathogenic Gram-negative bacteria isolated from Egyptian clinical settings

14 Sept 2023

Abstract excerpt

ABSTRACT Biosynthetic gene clusters (BGCs) are a subset of consecutive genes present within a variety of organisms to produce specialized metabolites (SMs). These SMs are becoming a cornerstone to produce multiple medications including antibacterial and anticancer agents. Natural products (NPs) also play a pivotal role in enhancing the virulence of ESKAPE pathogens ( Enterococcus faecium , Staphylococcus aureus ,...

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PMID: 37707241
DOI: 10.1128/spectrum.01344-23

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