A novel mutation in FK506 binding protein-like (FKBPL) causes male infertility.

Abstract excerpt

AIM: To perform a mutation analysis of FK506 binding protein-like (FKBPL) in patients with azoospermia. METHODS: DNA samples were isolated from the peripheral blood of 30 azoospermic male patients with normal 46 XY karyotype and 10 healthy controls. Multiplex polymerase chain reaction assays were used to evaluate Y microdeletions, and the patients without deletions were further analyzed. Sanger sequencing was...

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