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Article

[Mutation of KLHL-10 in idiopathic infertile males with azoospermia, oligospermia or asthenospermia].

Zhonghua nan ke xue = National journal of andrology - 1 Nov 2009

Qiu Qing-Ming, Liu Gang, Li Wei-Na, Shi Qiu-Wen, Zhu Fu-Xi, Lu Guang-Xiu

Abstract excerpt

OBJECTIVE: To investigate the relationship of the mutation of the spermatogenesis-associated gene KLHL-10 with azoospermia, oligospermia and asthenospermia. METHODS: Genomic DNA was extracted from the peripheral blood samples of 325 patients with idiopathic azoospermia (n = 11), oligozoospermia (n = 196) or asthenospermia (n = 118) and 100 fertile male controls. KLHL-10 mutations were detected for all the DNA...

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PMID: 20218307

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