Article
Prevalence of UL97 gene mutations and polymorphisms in cytomegalovirus infection in the colon associated with or without ulcerative colitis.
Scientific reports - 1 Jul 2021
Tamura Satoshi, Osawa Satoshi, Ishida Natsuki, Miyazu Takahiro, Tani Shinya, Yamade Mihoko, Iwaizumi Moriya, Hamaya Yasushi, Kosugi Isao, Furuta Takahisa, Sugimoto Ken
Abstract excerpt
Cytomegalovirus (CMV) reactivation in the colon is common in patients with severe ulcerative colitis (UC). Ganciclovir (GCV) resistance conferring CMV UL97 gene mutations have been reported in recent years. However, the prevalence of UL97 gene mutations in GCV-naive CMV infection in the colon remains unknown. We investigated the prevalence of CMV UL97 gene mutations in patients with colonic CMV infection...
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