Article
Comparison of cytomegalovirus (CMV) UL97 gene sequences in the blood and vitreous of patients with acquired immunodeficiency syndrome and CMV retinitis.
The Journal of infectious diseases - 1 Apr 2002
Hu Huiling, Jabs Douglas A, Forman Michael S, Martin Barbara K, Dunn J P, Weinberg David V, Davis Janet L
Abstract excerpt
Cytomegalovirus (CMV) resistance to ganciclovir occurs via mutations in the UL97 gene. CMV DNA, from vitreous and blood specimens and from culture isolates from 87 patients with acquired immunodeficiency syndrome and CMV retinitis who received a ganciclovir implant, was sequenced to identify the relationship between the UL97 DNA sequences in the eye and peripheral blood. There was 93.5% agreement between the UL97...
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